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Publications
The multiparametric MRI technology underpinning LiverMultiScan® was first published in two landmark papers from the University of Oxford, highlighting the utility for non-invasive diagnosis and staging of liver disease (Banerjee, R. et al. 2014-J. Hepatol) and prediction of clinical outcomes in patients with chronic liver disease (Pavlides, 2016-J. Hepatol.). Subsequent publications have demonstrated utility in fatty liver disease (Pavlides, 2016-Liver Int., Wilman, 2017, Eddowes, 2018) along with cost-effectiveness when incorporated into a clinical pathway (Blake, 2016).
In earlier posted publications there is mention of a LIF score which is a composite measure based on cT1, a metric provided by LiverMultiScan. LIF is a mapping of cT1 onto a 0-4 scale. cT1 has replaced LIF as the preferred metric for representing iron-corrected relaxation time of liver tissue. It is a direct metric shown to correlate with fibro-inflammation of liver tissue.
More of our publications are listed below.
Serum Matrix Metalloproteinase 7 Is a Diagnostic Biomarker of Biliary Injury and Fibrosis in Pediatric Autoimmune Liver Disease
Journal: Hepatology Communications
Publication Year: 2020
Volume/Issue: 4(11)
Pages: 1680 - 1693
Comparison of liver T1 relaxation times without and with iron correction in pediatric autoimmune liver disease
Journal: Pediatric Radiology
Publication Year: 2020
Volume/Issue: 50(7)
Pages: 935–942.
Relationship between magnetic resonance imaging spleen T1 relaxation and other radiologic and clinical biomarkers of liver fibrosis in children and young adults with autoimmune liver disease.
Journal: Abdominal Radiology
Publication Year: 2020
Volume/Issue: 45(11)
Pages: 3709–3715
Quantitative MRCP Imaging: Accuracy, Repeatability, Reproducibility, and Cohort-Derived Normative Ranges
Journal: Journal of Magnetic Resonance Imaging
Publication Year: 2020
Volume/Issue: 52(3)
Pages: 807–820
Differentiating pediatric autoimmune liver diseases by quantitative magnetic resonance cholangiopancreatography
Journal: Abdominal Radiology
Publication Year: 2020
Volume/Issue: 45(1)
Pages: 168-176
Diagnostic performance of quantitative magnetic resonance imaging biomarkers for predicting portal hypertension in children and young adults with autoimmune liver disease.
Journal: Radiology
Publication Year: 2019
Volume/Issue: 49(3)
Pages: 332-341
Stratification of biliary disease with quantitative MRCP (MRCP+)
Journal: Hepatology
Publication Year: 2018
Volume/Issue: Volume 68, Issue 1
Pages: 1111 Abstract 1952
Multi-parametric MRI imaging in a heterogeneous liver disease: cross-sectional evaluation of a cohort of patients with PSC
Journal: Hepatology
Publication Year: 2018
Volume/Issue: Volume 68, Issue 1
Pages: 1090 Abstract 1917
Matrix Metalloproteinase 7 (MMP7) as a Biomarker of Sclerosing Cholangitis in Pediatric Autoimmune Liver Disease
Journal: Hepatology
Publication Year: 2018
Volume/Issue: Volume 68
Pages: 115 Abstract 183